皮傲宁Pionin

简介：常见于日本非处方药（OTC）作为祛痘成分使用。皮傲宁具有极强的抗菌活性（破坏细菌真菌细胞膜，对丙酸痤疮杆菌有极好的效果）；还可抑制黑色素形成；强效但安全性极高；多用于祛痘、美白祛斑产品。

Introduction: Commonly used in Japanese over-the-counter (OTC) as an anti-acne ingredient. Pionin shows extremely strong antibacterial activity (destroys the cell membranes of bacteria and fungi and has an excellent effect on propionibacterium acnes); can also inhibit the formation of melanin; potent but extremely safe; mostly used in products for acne removal and whitening.

化学名称：聚季铵盐-73

Chemical name: Polyquaternium-73

英文名称：PIONIN;BIOXYNE;QUATERNIUM-73

CAS： 15763-48-1

性状：淡黄色至黄色晶状粉末,无气味

Character: Light yellow to yellow crystalline powder, odorless

用途：具有抗菌活性的粉刺、痤疮抑制剂；可用作防腐剂，对细菌、葡萄球菌、大肠杆菌等有极强杀灭能力，防腐性能优于尼泊金酯类；此外，可抑制黑色素的生成。临床研究显示, 它对痤疮杆菌mic=0.00002%，使用两周后皮疹可减50% ，在用量为0.1ppm时完全抑制黑色素的形成，优于曲酸。安全性高，对热、光稳定性好，在ph5.5至8.0范围内稳定。用量低，性价比高。 

Purpose: Pimple and acne inhibitors with antibacterial activity; can be used as preservatives, has a strong killing ability against bacteria, staphylococci, Escherichia coli, etc., and its antiseptic property is better than parabens; in addition, it can inhibit the generation of melanin. Clinical research shows that it has a mic = 0.00002% for acne bacilli, and the rash can be reduced by 50% after two weeks of use. When the dosage is 0.1ppm, it can completely inhibit the formation of melanin, and is better than kojic acid. High safety, good thermal and light stability, stable in the range of ph5.5 to 8.0. Low dosage and high cost performance.  

使用方法：适用于各种护肤品，推荐用于控油祛痘、抗粉刺护肤品及男士护肤品中；建议先用乙醇、丁二醇、戊二醇预溶后再加入。 

Directions: It is suitable for all kinds of skin care products, and recommended for oil control, acne-removal, and anti-acne skin care products and men's skin care products; it is recommended to pre-dissolve with ethanol, butanediol or pentanediol before adding. 

建议用量：0.001-0.002%。  

Recommended dosage: 0.001-0.002%.  

功能作用：低用量时即可通过瓦解微生物细胞膜和细胞膜，降低细胞内部活性的作用，从而使细菌生长受到抑制或是失去生存能力，广谱抑菌，0.00002%就能抑制痤疮丙酸杆菌的生长。有效抑制酪氨酸酶，抑制黑色素形成，达到美白功效。

可用于：清洁产品（洗面奶、洗发水）；祛痘产品、油性皮肤护理产品；美白产品；防腐促进剂

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